项目成员

李胜,博士,中科院上海生科院植物生理生态研究所研究员,杰青,百人优秀,上海市优秀学术带头人,中科院重点实验室副主任。

2000年获中国科学院上海昆虫研究所动物学博士学位,2006年从约翰霍普金斯大学博士后回国。长期从事昆虫发育遗传学研究,以家蚕和果蝇做模式昆虫,在脂肪体发育和脂肪代谢研究领域取得了一系列进展。获得了"李汝祺动物遗传奖"和"明治生命科学奖"等奖励。在Autophagy、Annual Review of Entomology、Cell Research、Development等SCI期刊上发表论文51篇,其中通讯作者论文27篇;授权和申请专利2项。

实验室网站:http://sedu.sibs.ac.cn/daoshi/2004/display.asp?ID=114

近5年10篇代表性研究论文(*通讯作者)

1.Xia, Q.#,*, Li, S.#, Feng, Q.#, 2014. Advances in silkworm studies accelerated by the Bombyx genome. Annual Review of Entomology, 59:213-236. (# equal contribution; * an invited review). (IF 13.589)

2.Tian, L., Ma, L., Guo, E., Deng, X., Ma, S., Xia, Q., Cao, Y., Li, S.*, 2013. 20-hydroxyecdysone upregulates Atg genes to induce autophagy in the Bombyx fat body. Autophagy, 9:1167-1182. (IF 12.042)

3.Ma, L., Shi, M., Chen, X-X., Li, S.*, 2013. Ras1CA upregulates bcpi for inhibiting cathepsin activity to prevent tissue destruction of the Bombyx posterior silk gland. Journal of Proteome Research, 12:1924-1934. (IF 5.056)

4.Wang, S., Wang, J., Sun, Y., Song, Q., Li, S.*, 2012. PKC-mediated USP phosphorylation at Ser35 modulates 20-hydroxyecdysone signaling in Drosophila. Journal of Proteome Research, 11:6187-6196. (IF 5.056)

5.Ma, L., Xu, H., Zhu, J., Ma, S., Liu, Y., Jiang, R-J., Xia, Q, Li, S.*, 2011. Ras1CA overexpression in the posterior silk gland improves silk yield. Cell Research, 21:934-943. (IF 10.526)

(Highlighted by Belles, X. 2011 Cell Research 21:862-863)

(李胜,马俐,夏庆友,徐汉福,2010. 一种提高蚕丝产量的转基因方法。专利授权号ZL201010118072.8)

6.Huang, J., Tian, L., Abdou, M., Wen, D., Wang, Y., Li, S.*, Wang, J., 2011. DPP-mediated TGF-β signaling regulates juvenile hormone biosynthesis by upregulating expression of JH acid methyltransferase. Development, 138:2283-2291. (IF 6.208)

7.Li. S.*, 2010. Identification of iron-loaded ferritin as an essential mitogen for cell proliferation and postembryonic development in Drosophila. Cell Research, 20:1148-1157. (IF 10.526)

8.Wang, S., Liu, S., Liu, H., Wang, J., Zhou, S., Liu, Y., Jiang, R-J., Bendena, W.G., Li, S.*, 2010. The insect steroid hormone 20-hydroxyecdysone reduces food consumption resulting in fat body lipolysis during molting and pupation. Journal of Molecular Cell Biology, 2:128-138. Cover Story (IF 7.308)

9.Tian, L., Guo, E., Diao, Y., Wang, S., Liu, S., Cao, Y., Jiang, R-J., Ling, E., Li, S.*,2010. Developmental regulation of glycolysis by 20-hydroxyecdysone and juvenile hormone in fat body tissues of the silkworm, Bombyx mori. Journal of Molecular Cell Biology, 2:255–263. (IF 7.308)

10.Liu, Y., Sheng, Z., Liu, H., Wen, W., He, Q., Wang, S., Shao, W., Jiang, R-J., An, S., Sun, Y., Bendena, W.G., Wang, J., Gilbert, L.I., Wilson, T.G., Song, Q., Li, S.*, 2009. Juvenile hormone counteracts the bHLH-PAS transcriptional factor MET and GCE to prevent caspase-dependent programmed cell death in Drosophila. Development 136: 2015-2025. (IF 6.208)