章张，中科院北京基因组研究所“百人计划“研究员，博士生导师。

Email:zhangzhang(AT)big.ac.cn

学习经历：

1998-2002 宁夏大学 计算机科学 学士

2002-2004 南京理工大学 计算机科学 硕士

2004-2007 中国科学院计算技术研究所 计算机科学 博士

工作经历：

2007-2009 美国耶鲁大学（Yale University） 博士后 （Postdoctoral Associate）

2009-2011 沙特阿卜杜拉国王理工大学（King Abdullah University of Science and Technology） 研究科学家（Research Scientist）

2011-至今 中国科学院北京基因组研究所"百人计划"研究员

主要研究领域：

分子序列进化建模与分析、海量生物数据整合与信息挖掘

承担科研项目情况：

代表论著：

1. Zhang, Z.*, Sang, J. Ma, L.N., Wu, G., Wu, H., Huang, D.W., Zou, D., Liu, S.Q., Li, A., Hao, L.L., Tian, M., Xu, C., Wang, X.M., Wu, J.Y., Xiao, J.F., Dai, L., Chen, L.-L., Hu, S.N., and Yu, J. (2014) RiceWiki: a wiki-based database for community curation of rice genes, Nucleic Acids Research, doi: 10.1093/nar/gkt926, in press.

2. Wu, J.Y., Xiao, J.F., Wang, L.P., Zhong, J., Yin, H.Y., Wu, S.X., Zhang, Z., Yu, J. (2013) Systematic analysis of intron size and abundance parameters in diverse lineages, Sci China Life Sci, 56:1–7.

3. Zhang, Z., Wong, G.K. and Yu, J. (2013) Protein coding, In: eLS. John Wiley & Sons Ltd, Chichester.

4. Dai, L., Tian, M., Wu, J.Y., Xiao, J.F., Wang, X.M., Townsend, J.P. and Zhang, Z.* (2013) AuthorReward: increasing community curation in biological knowledge wikis through automated authorship quantification, Bioinformatics, 29(14):1837-1839.

5. Ma, L.N., Bajic, V.B., and Zhang, Z.* (2013) On the classification of long non-coding RNAs, RNA Biology, 10(6):1-10.

6. Tong, X., Yang, Y., Wang, W., Bai, Z., Ma, L., Zheng, X., Sun, H., Zhang, Z., Zhao, M., Yu, J., Ge, R.L.(2013) Expression profiling of abundant genes in pulmonary and cardiac muscle tissues of Tibetan Antelope (Pantholops hodgsonii), Gene, pii: S0378-1119(13)00245-X. doi: 10.1016.

7. Dai, L., Xu, C., Tian, M., Sang, J., Zou, D., Li, A., Liu, G.C., Chen, F., Wu, J.Y., Xiao, J.F., Wang, X.M., Yu, J., and Zhang, Z.* (2013) Community intelligence in knowledge curation: an application to managing scientific nomenclature, PLoS ONE, 8(2), e56961.

8. Zhang, Z., and Yu. J. (2013) Does the genetic code have a eukaryotic origin? Genomics Proteomics Bioinformatics, 11(1):41-55.

9. Chen, M., Xiao, J.F., Zhang, Z., Liu, J., Wu, J.Y., and Yu, J. (2013) Identification of human HK Genes and gene expression regulation study in cancer from transcriptomics data analysis, PLoS ONE, 8(1), e54082.

10. Dai, L., Gao, X., Guo, Y., Xiao, J.F. and Zhang, Z.* (2012) Bioinformatics clouds for big data manipulation, Biology Direct, 7, 43.

11. Zhang, Z. and Yu, J. (2012) The pendulum model for genome compositional dynamics: from the four nucleotides to the twenty amino acids, Genomics Proteomics Bioinformatics, 10(4), 175-180.

12. Wu, H., Qu, H.Z, Wan, N., Zhang, Z., Hu, S.N. and Yu, J. (2012) Strand-biased gene distribution in bacteria is related to both horizontal gene transfer and strand-biased nucleotide composition, Genomics Proteomics Bioinformatics, 10(4), 186-196.

13. Cui, P., Liu, W., Zhao, Y., Lin, Q., Zhang, D., Ding, F., Xin, C., Zhang, Z., Song, S., Sun F et al (2012) Comparative analyses of H3K4 and H3K27 trimethylations between the mouse cerebrum and testis. Genomics Proteomics Bioinformatics, 10(2), 82-93.

14. Cui, P., Ding, F., Lin, Q., Zhang, L., Li, A., Zhang, Z., Hu, S. and Yu, J. (2012) Distinct contributions of replication and transcription to mutation rate variation of human genomes, Genomics Proteomics Bioinformatics, 10(1), 4-10.

15. Zhang, Z.*, Xiao, J., Wu, J., Zhang, H., Liu, G., Wang, X. and Dai, L. (2012) ParaAT: a parallel tool for constructing multiple protein-coding DNA alignments, Biochem Biophys Res Commun, 419(4), 779-781.

16. Zhang, Z., Li, J., Cui, P., Ding, F., Li, A., Townsend, J.P. and Yu, J. (2012) Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance, BMC Bioinformatics, 13, 43.

17. Wu, H., Zhang, Z., Hu, S. and Yu, J. (2012) On the molecular mechanism of GC content variation among eubacterial genomes, Biology Direct, 7, 2.

18. Zhang, Z., Bajic, V.B., Yu, J., Cheung, K.-H. and Townsend, J.P. (2011) Data integration in bioinformatics: current efforts and challenges. In Mahdavi, M.A. (ed), Bioinformatics - Trends and Methodologies. InTech - Open Access Publisher, Rijeka, Croatia. Available from: http://www.intechopen.com/articles/show/title/data-integration-in-bioinformatics-current-efforts-and-challenges.

19. Zhang, Z. and Yu, J. (2011) On the organizational dynamics of the genetic code, Genomics Proteomics Bioinformatics, 9(1-2), 21-29.

20. Zhang, Z. and Yu, J. (2010) Modeling compositional dynamics based on GC and purine contents of protein-coding sequences, Biology Direct, 5, 63.

社会任职：

1、编委成员：Biology Direct (2013—) 2、学术编辑（Academic Editor）: Plos ONE (2012—), PeeJ (2013—) 3、副主编（Associate Editor-in-Chief）: Genomics, Proteomics & Bioinformatics (2012-) 4、评审编辑（Review Editor）: Frontiers in Statistical Genetics and Methodology (2011-) 5、评审员: Bioinformatics, BMC Bioinformatics, BMC Evolutionary Biology, BMC Systems Biology, Briefings in Bioinformatics, Chinese Bulletin of Life Sciences, Current Bioinformatics, Evolutionary Bioinformatics, Genomics Proteomics & Bioinformatics, In Silico Biology, Journal of Molecular Evolution, Molecular Biology and Evolution, PLoS ONE 6、会员: Bioinformatics, Genetics Society of China, International Society of Computational Biology (ISCB), Society for Molecular Biology and Evolution (SMBE)